How did the European Reformation affect the relationship between

How did the European Reformation affect the relationship between church and state?
A、It strengthened the power of the church over secular rulers.
B、It led to the separation of church and state in many countries.
C、It had no significant impact on the relationship between church and state.
D、It resulted in a unified Christian front against non-Christian powers.
【正确答案】：B
【题目解析】：It led to the separation of church and state in many countries.